Research at the AVNduallogo

Alberta Vision Net brings together researchers at the Universities of Alberta and Calgary to advance the understanding and treatment of ocular disease. With investigators from more than ten Departments, our network integrates ophthalmology and molecular biology with the following major objectives:

  • To foster fundamental and translational research to improve understanding and treatment of disease
  • Explore high impact novel research ideas, that offer the realistic prospect of fresh therapeutic approaches
  • Provide a rich cross-disciplinary environment and so offer outstanding training for fellows, residents and students

News

Special Issue on Ophthalmic Genetics: Vision in 2020

September 29, 2020

The recent special issue of the American Journal of Medical Genetics; Seminar in Medical Genetics (Volume 184, Issue 3) includes contributions from four AVN labs: Waskiewicz, Lehmann, Walter, and MacDonald. Check out the issue to learn more about ocular coloboma, retinal dystrophies, and more: AJMG Ocular Genetics

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Congrats to Nate Nadolski

September 16, 2020

Nate defended his MSc thesis (Form and Function of Photoreceptors in kcnv2 Mutant Zebrafish: Implications for the Human Disease KCNV2 Retinopathy) last Thursday. After giving a great talk, he passed without revisions! Congrats to Nate on being the first student to graduate from the Hocking lab, and all the best to him as he starts his first year of medical school at the University of Alberta.

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Highlights from the Casey Lab

August 31, 2020

Darpan Malhotra defended his PhD in June 2019, with Bob Molday doubling as his external examiner and our AVN Research Day keynote speaker (see photo of Bob, Darpan, and Joe). The Casey lab is still publishing papers based on Darpan’s impressive body of work about the SLC4A11 corneal transporter. To learn more, check out these publications:

Malhotra, D. and Casey, J.R. (2020) Molecular Mechanisms of Fuchs and Congenital Hereditary Endothelial Corneal Dystrophies Reviews in Physiology, Biochemistry and Pharmacology, In Press.

Malhotra, D., Jung,M., Fecher-Trost, C., Lovatt, M., Peh, G.S.L, Noskov, S., Mehta, J.S., Zimmermann, R., and Casey, J.R. (2020) Defective Cell Adhesion Function of Solute Transporter, SLC4A11, in Endothelial Corneal Dystrophies, Human Molecular Genetics, 29, 97-116.

Malhotra, D., Chiu, A.M., Loganathan, S.K., Lukowski, C.M. and Casey, J.R. (2019) Identification of SLC4A11 Translational Product in Human Cornea, Scientific Reports, 9, 9681.

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Alberta Vision Net is made possible by generous support from the University of Alberta Faculty of Medicine and Dentistry, and the Royal Alexandra Hospital Foundation.

University of Alberta
7-030 Katz Centre
Edmonton AB, T6G 2E1

University of Alberta
7-030 Katz Centre
Edmonton AB, T6G 2E1